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Dostinex 0,5 mg Pfizer Labs
6.00 € – 48.00 €
This instruction is just a short supplement to the official instruction. The site administration does not bear any responsibility for possible risks associated with self-medication. Before buying a device, consult your doctor.
Cabergoline (active ingredient) – inhibits the secretion of prolactin, in addition, enhances libido and erection, significantly reduces the recovery time between intercourse, and also lowers blood pressure. Cabergoline belongs to the derivatives of ergot alkaloids, according to the mechanism of action – an agonist of dopamine (D2) receptors. It is a more modern and safer analogue of bromocriptine.
Packaging video review Dostinex 0,5 mg Pfizer Labs
Mechanism of action
The main mechanism of action of cabergoline is the activation of D2 receptors, which are located on the lactotrophic cells of the pituitary gland. Excitation of dopamine receptors in this area leads to a decrease in the secretory function of prolactin-producing cells.
In addition, interaction with other receptors was established: D3, D4, 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, α2B. Antagonism with α2B receptors further explains the positive effect on erectile function (the corpus cavernosum expands).
APPLICATION IN BODYBUILDING
During the course of progestin anabolic steroids (nandrolone, trenbolone): 0.25 mg (1/2 tab.) Every 7-21 days, starting from the third or fourth week of the course, when the concentration of ACC is approaching the maximum. The optimal dose and frequency of administration is selected under the control of prolactin level analyzes, since the effect of the drug differs and depends on the individual characteristics of the organism.
With an increase in the level of prolactin above the permissible frequency of admission increases: 0.25 mg, every 4 days. It is advisable to perform a control analysis of prolactin after two doses with subsequent correction of the scheme.
The drug is taken both with food and on an empty stomach.
A study in 200 patients with parkinsonism using high doses of cabergoline (0.5 mg every day) reported the following side effects:
Digestive system (most common): nausea, constipation, dry mouth, dyspepsia
Nervous system: insomnia, dizziness, depression, distortion of consciousness
Cardiovascular system: drop in blood pressure, peripheral edema, rhythm disturbance, valve damage, pericarditis
Immune system disorders: infrequently – hypersensitivity reaction, skin rash.
From the hematopoietic system: infrequently – erythromelalgia.
From the respiratory system: often – shortness of breath, infrequently – pleural effusion, pulmonary fibrosis, nosebleeds.
When using low dosages, side effects are rare or completely absent. On the forums, depressed mood and loss of appetite are most often reported.
It is not recommended to take more than one tablet per week (with the exception of highly elevated prolactin levels).